Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217179 | Tetrahedron | 2014 | 9 Pages |
Abstract
A small family of P,Pâ-bidentate C1-symmetric ligands containing 1,3,2-diazaphospholidine rings with stereogenic phosphorus atoms has been prepared. Palladium catalytic systems with these phosphine-diamidophosphites afforded 95% and 63% ees in asymmetric allylic substitution and desymmetrization processes, respectively. The influence of the nature of both the phosphine and diamidophosphite moieties of these compounds on the enantioselectivity is discussed. The 'mixed-ligand approach' in Pd-catalyzed asymmetric allylation with participation of some new Pâ-monodentate diamidophosphites and PPh3 is also considered.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Konstantin N. Gavrilov, Alexei A. Shiryaev, Sergey V. Zheglov, Vladislav K. Gavrilov, Nikolay N. Groshkin, Marina G. Maksimova, Alexandr N. Volov, Ilya A. Zamilatskov,