Article ID Journal Published Year Pages File Type
5217195 Tetrahedron 2014 7 Pages PDF
Abstract

Concise and efficient enantioselective total syntheses of heliannuols B and D have been accomplished using chirality transfer through a Lewis acid-promoted Claisen rearrangement for the construction of the C7 tertiary stereogenic center and a relay ring-closing metathesis for assembling the dihydrobenzo[b]oxepine backbone of the natural products as the key steps.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry