Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217215 | Tetrahedron | 2013 | 5 Pages |
Abstract
The direct C-H arylation of a heteroarene with aryl bromides has been achieved under the catalysis of magnetic nanoparticles. In the presence of bimetallic Pd-Fe3O4 heterodimer nanocrystals (1 mol % in palladium), the reaction of imidazo[1,2-a]pyridine with various aryl bromides gives the corresponding arylated products with exclusive C3-selectivity. The highly regioselective method is applicable to a wide range of aryl bromides with varying electronic and steric properties. The Pd-Fe3O4 nanocrystals can be recoverable by simple magnetic separation and have been recycled ten times without loss of catalytic activity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jaewoo Lee, Jooyoung Chung, Sang Moon Byun, B. Moon Kim, Chulbom Lee,