Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217223 | Tetrahedron | 2013 | 6 Pages |
Abstract
Herein we report a silver-catalyzed ring-opening of cyclopropenes by addition of amines. This transformation is thought to occur via an argentocarbenium intermediate and affords tertiary α-branched allylic amines in good yields and high regioselectivity. The protocol applies to various primary and secondary amines, as well as sterically hindered cyclopropenes. Friedel-Crafts cyclization of the cationic intermediate occurs as a competitive pathway to form methyl-indene.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Diem T.H. Phan, Vy M. Dong,