Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217267 | Tetrahedron | 2013 | 8 Pages |
Abstract
A series of bispirooxindole derivatives have been synthesized via a cascade Michael-Cyclization reaction between isothiocyanato oxindoles and methyleneindolinones with high yields (up to 98%) and excellent diastereoselectivities (up to >95:5 dr) under mild conditions. The structure and effect on the reaction of less studied 4-substituted methyleneindolinones have also been investigated.
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