Article ID Journal Published Year Pages File Type
5217267 Tetrahedron 2013 8 Pages PDF
Abstract

A series of bispirooxindole derivatives have been synthesized via a cascade Michael-Cyclization reaction between isothiocyanato oxindoles and methyleneindolinones with high yields (up to 98%) and excellent diastereoselectivities (up to >95:5 dr) under mild conditions. The structure and effect on the reaction of less studied 4-substituted methyleneindolinones have also been investigated.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry