Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217305 | Tetrahedron | 2013 | 7 Pages |
Abstract
Five new indole alkaloids, voacalgines A-E (1-5) consisting of a C-mavacurine type of skeleton with 2,3-dihydroxybenzoate moiety, a macroline-type of skeleton, or a macroline-type of skeleton with C6 unit, were isolated from the bark of Voacanga grandifolia. Their relative structures were determined by means of NMR data. Voacalgine A showed moderate cell growth inhibitory activities against HL-60 and HCT116 cells.
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Physical Sciences and Engineering
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Organic Chemistry
Authors
Yusuke Hirasawa, Hiroko Arai, Abdul Rahman, Idha Kusumawati, Noor Cholies Zaini, Osamu Shirota, Hiroshi Morita,