Article ID Journal Published Year Pages File Type
5217305 Tetrahedron 2013 7 Pages PDF
Abstract

Five new indole alkaloids, voacalgines A-E (1-5) consisting of a C-mavacurine type of skeleton with 2,3-dihydroxybenzoate moiety, a macroline-type of skeleton, or a macroline-type of skeleton with C6 unit, were isolated from the bark of Voacanga grandifolia. Their relative structures were determined by means of NMR data. Voacalgine A showed moderate cell growth inhibitory activities against HL-60 and HCT116 cells.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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