| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217312 | Tetrahedron | 2013 | 7 Pages |
Abstract
A one-pot procedure was developed for the synthesis of isoindolin-1-imine derivatives by a simple three-component condensation of 2-cyanobenzaldhyde, ammonium acetate, and 4-hyroxycoumarin derivatives or 1,3-dicarbonyl compounds or 4-hydroxyquinolin-2(1H)-one in ethanol under reflux for 20-60Â min with excellent yields. The advantages of this procedure are operational simplicity, excellent yields, and short reactive time, without catalyst, easy workup, and green environmental impact.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Khangvan Pham, Zhongguo Zhang, Sida Shen, Lei Ma, Lihong Hu,