Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217340 | Tetrahedron | 2013 | 8 Pages |
Abstract
Polyhydroxylated pyrrolizidines bearing a methyl group at C-5 have been synthesized by 1,3-dipolar cycloaddition of five membered cyclic nitrones with methyl vinyl ketone followed by a N-O reductive cleavage and in situ intramolecular reductive amination. The stereochemistry of the obtained compounds is examined in relation to the reactions mechanism.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Petros Gkizis, Nikolaos G. Argyropoulos, Evdoxia Coutouli-Argyropoulou,