| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217412 | Tetrahedron | 2014 | 8 Pages |
Abstract
A variety of tetrahydro-1H-carbazol-1-ones and analogs were conveniently synthesized from the reaction of the corresponding 2-(phenylamino)cyclohex-2-enone with hypervalent iodine reagent PhI(OCOCF3)2 (PIFA), through a direct intramolecular oxidative C(sp2)-C(sp2) bond formation. This approach realized the construction of the biologically important tetrahydro-1H-carbazol-1-one and tetrahydrocyclohepta[b]indol-6(5H)-one skeletons. The mechanism of the process was proposed and briefly discussed.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hao Shi, Tianjian Guo, Daisy Zhang-Negrerie, Yunfei Du, Kang Zhao,