Article ID Journal Published Year Pages File Type
5217419 Tetrahedron 2014 6 Pages PDF
Abstract

Asymmetric aldol reactions of aliphatic ketones or aldehydes with aromatic aldehydes or isatins were catalyzed by a very simple and flexible N-(2,6-difluorophenyl)-l-valinamide. Interestingly, stereochemical course of the reaction of hydroxyacetones or α-branched aliphatic aldehydes as aldol donors was different from that of cycloalkanones.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry