Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217419 | Tetrahedron | 2014 | 6 Pages |
Abstract
Asymmetric aldol reactions of aliphatic ketones or aldehydes with aromatic aldehydes or isatins were catalyzed by a very simple and flexible N-(2,6-difluorophenyl)-l-valinamide. Interestingly, stereochemical course of the reaction of hydroxyacetones or α-branched aliphatic aldehydes as aldol donors was different from that of cycloalkanones.
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