| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217478 | Tetrahedron | 2013 | 7 Pages |
Abstract
The reaction of 1-bromo-2-(1-isothiocyanatoalkyl)benzenes, which are easily derived from 2-bromophenyl ketones or (2-bromophenyl)methanamine, with butyllithium generates 1-(1-isothiocyanatoalkyl)-2-lithiobenzenes, which immediately underwent intramolecular cyclization to give rise to the corresponding 3-substituted and 3,3-disubstituted 2,3-dihydro-1H-isoindole-1-thiones in good yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kazuhiro Kobayashi, Yuki Yokoi, Tatsuya Nakahara, Naoki Matsumoto,