Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217481 | Tetrahedron | 2013 | 9 Pages |
Abstract
The synthesis of different protected alternariol derivatives using intramolecular cyclization of iodoresorcylic acid phenyl esters by palladium-catalyzed C-H activation as key step is presented. Furthermore, chemical sulfation and glucosylation were applied for the preparation of conjugated Alternaria mycotoxins. These compounds are suspected to be formed during metabolism in contaminated plants. Therefore, all synthetic conjugates prepared within this work serve as reference materials for further studies in the fields of bioanalytics and toxicology of mycotoxins.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hannes Mikula, Philipp Skrinjar, Barbara Sohr, Doris Ellmer, Christian Hametner, Johannes Fröhlich,