Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217526 | Tetrahedron | 2013 | 6 Pages |
Abstract
An efficient one-pot synthesis of perfluoroalkylated ring-fused 2-pyridones by three-component reaction of diamine, ketene dithioacetal, and methyl 2-perfluoroalkynoate in EtOH is reported. This protocol has the advantages of easiness, higher yields, and shorter reaction time. A plausible mechanism for this type of cyclization is proposed.
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