| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217550 | Tetrahedron | 2013 | 5 Pages |
Abstract
The first novel protocol of the synthesis of 2-substituted benzo[f]isoindole-4,9-dione framework via the one-pot, 1,3-dipolar cycloaddition of quinones, paraformaldehyde and N-substituted amino ester hydrochlorides in the present of iodine at refluxing acetonitrile was reported. All these reactions proceed with good to excellent yields. The promising results obtained 1,3-dipolar cycloaddition will have the potential application in natural product exhibiting important biological activities.
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Related Topics
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