Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217561 | Tetrahedron | 2013 | 10 Pages |
Abstract
Novel phosphanucleosides containing a 3-hydroxy-1-hydroxymethylphospholane 1-oxide ring were synthesized as compounds with potential biological activity. A double Arbuzov reaction was employed to prepare a phospholene precursor, which was then converted into an epoxide and subsequently into racemic phosphanucleoside via nucleobase construction.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
OndÅej Páv, Eva ZbornÃková, MiloÅ¡ BudÄÅ¡Ãnský, Ivan Rosenberg,