| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217587 | Tetrahedron | 2013 | 6 Pages |
Abstract
Metal-free synthesis of 3,3-disubstituted oxindoles utilizing N-arylacrylamides and simple alcohols is developed. It provides an efficient method for preparing a series of hydroxyl-containing oxindole derivatives. This reaction is proposed to proceed through oxidative radical cyclization mechanism. The remarkable features of the reaction are metal-free condition and excellent functional group tolerance.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
