| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217672 | Tetrahedron | 2013 | 6 Pages |
Abstract
A novel coumarin-derived fluorescent probe, FCP, was designed for Zn2+ quantification based on the photo-induced electron transfer (PET) mechanism. This probe selectively and sensitively detects Zn2+ in aqueous solution with wide pH range. Large fluorescence enhancement (13-fold) was observed upon the addition of Zn2+. FCP also displays excellent cell permeability in HeLa cell model and very low cytotoxicity to HEK-293 cell model.
Graphical abstractA novel water-soluble Zn2+ fluorescent probe, FCP, was designed by hybrid coumarin and di-2-picolylamine. FCP displayed excellent cell permeability in HeLa cell model and very low cytotoxicity to HEK-293 cells.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
