Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217748 | Tetrahedron | 2013 | 6 Pages |
Abstract
A facile and efficient enantioselective route for the synthesis of d-ribo-phytosphingosine (1a) and sphinganine (1b) has been developed employing commercially available and cheap starting material trans-cinnamaldehyde 2. The synthetic strategy features the Sharpless kinetic resolution, regioselective epoxide opening and Wittig olefination as the key steps.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Thongam Joymati Devi, Bishwajit Saikia, Nabin C. Barua,