Article ID Journal Published Year Pages File Type
5217753 Tetrahedron 2013 10 Pages PDF
Abstract

Simple firefly luciferin analogs emitting blue, green, and red light were developed. The longest emission maximum was observed at 675 nm, which belongs to the NIR biological window (650-900 nm), useful for deep site bioimaging of living animals. The analogs showed a slow rise of emission intensity compared with the rapid emission of natural luciferin. The light emission of the adenylated analogs was strongly enhanced compared with those of analogs themselves.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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