Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217804 | Tetrahedron | 2013 | 6 Pages |
Abstract
A simple approach to the modification of BODIPY nucleus has been developed. The method is based on the reaction of acetaldehyde-substituted dye with primary amines followed by cyclization of enamine intermediates. This procedure allowed preparing a series of new BODIPY derivatives with functional substituents useful for various practical purposes, including bioconjugation and other biomedical applications. The synthesized BODIPYs annealed to a pyridone fragment are stable compounds and intense fluorophores with emission maximum around 615 nm. This λem may be red-shifted by the introduction of styryl substituent.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yuriy V. Zatsikha, Viktor P. Yakubovskyi, Mykola P. Shandura, Igor Ya Dubey, Yuriy P. Kovtun,