Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217809 | Tetrahedron | 2013 | 7 Pages |
Abstract
The synthesis of α-sulfanyl, α-sulfonyl, and α-phosphono carboxylates has been achieved using a two-step procedure involving the in-flow generation of diazoesters from sulfonylhydrazones, via Bamford-Stevens elimination, and then subsequent S-H, sulfinate, and P-H carbene insertion reactions. The method for α-sulfonyl ester is particularly noteworthy as it represents a very atom economic ('green') way to access the products, and it completely avoids the use of alkyl halides.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hannah E. Bartrum, David C. Blakemore, Christopher J. Moody, Christopher J. Hayes,