Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217835 | Tetrahedron | 2013 | 10 Pages |
Abstract
N-Benzylcinnamanilides cyclise with triflic acid to form 1-benzyl-4-aryl-2,4-dihydro-1H-quinolin-2-ones and 2,5-diaryl-benzazepin-3-ones. The product ratio is determined by the preferred orientation of the amide and by the electronics of the substituents. With ortho-substituted anilides, N-debenzylation also occurs to give 4-aryl-2,4-dihydro-1H-quinoline-2-ones.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Frank D. King, Stephen Caddick,