| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217839 | Tetrahedron | 2013 | 8 Pages |
Abstract
The stereoselective total synthesis of (â)-brevisamide, a novel marine cyclic ether alkaloid isolated from dinoflagellate karenia brevis is described. The key steps involved in this synthesis are the Sharpless asymmetric epoxidation and regioselective ring opening of chiral epoxide by Gilman's reagent. The tetrahydropyran core has been constructed by an intramolecular SN2 cyclisation.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.S. Yadav, N. Mallikarjuna Reddy, Md. Ataur Rahman, A.R. Prasad, B.V. Subba Reddy,