| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217898 | Tetrahedron | 2013 | 7 Pages |
Abstract
The aqueous reaction of arylidene pyruvic acids (APAs) with arylamines or urea under refluxing conditions leading to the formation of 3-(amino)-5-aryl-furan-2(5H)-one, without catalyst, is described. Also (E)-4-(4-chlorophenyl)-2-oxobut-3-enoic acid reacts with 1,2-phenylenediamine to form (E)-3-(4-chlorostyryl)quinoxalin-2(1H)-one under the same conditions. Excellent yields were observed after filtration of the product and washing with brine solution.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Morteza Shiri, Majid M. Heravi, Bita Soleymanifard, Hendrik G. Kruger, Mohammad Ali Zolfigol,