| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217905 | Tetrahedron | 2013 | 8 Pages |
Abstract
Novel regioisomers of trifluoromethylated cyclopropanes have been synthesized by Michael addition and nucleophilic cyclization process. The reaction was carried out with the trifluoromethylcrotonate 6 and nucleophilic reagents. Fluorinated cyclopropanes were obtained with good to excellent diastereoselectivities. Furthermore, interesting constrained building blocks have emerged from this methodology.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Massaba Keita, Rocco De Bona, Mickael Dos Santos, Olivier Lequin, Sandrine Ongeri, Thierry Milcent, Benoit Crousse,