Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217960 | Tetrahedron | 2013 | 7 Pages |
Abstract
The total synthesis of the unusual 4-pyridone marine metabolite lodopyridone has been achieved by late stage manipulation of the related 4-pyrone. Key reactions include a Suzuki–Miyaura coupling to form the tetracyclic core and a modified Corey–Ganem–Gilman reaction to install the ethanolamide side-chain.
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