Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217963 | Tetrahedron | 2013 | 5 Pages |
Abstract
A simple, green and efficient protocol was developed using β-cyclodextrin as a solid catalyst for the solvent-free synthesis of various Biginelli adducts. The advantages of our protocol included the following: (i) a metal-free methodology; (ii) high yields; (iii) simple and efficient work-up procedures; (iv) improved results under solvent-free conditions. β-cyclodextrin-catalyzed the Biginelli reactions for various aldehydes, demonstrating that it is an efficient and eco-friendly catalyst for the preparation of heterocyclic compounds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Natália Aparecida Liberto, Sarah de Paiva Silva, Ãngelo de Fátima, Sergio Antonio Fernandes,