| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5218043 | Tetrahedron | 2013 | 7 Pages |
Abstract
1,5,7-Triazabicyclo[4.4.0]dec-1-ene (TBD) and 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-1-ene (MTBD) promote the efficient formation of sulfonium ylides from sulfonium salts in the Corey-Chaykovsky epoxidation of aldehydes and provide excellent yields of the corresponding epoxides. This reaction protocol can be further adapted to allow for the development of both sequential and tandem-oxidation-epoxidation protocols from aldehydes generated in situ by manganese dioxide (MnO2) or barium manganate (BaMnO4) mediated oxidation reactions.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
David J. Phillips, Joseline L. Kean, Andrew E. Graham,