Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5218102 | Tetrahedron | 2013 | 7 Pages |
Abstract
A solvent-free S/Co(NO3)2 cascade catalyzed cyclocondensation reaction of aromatic nitriles with 3-amino-1-propanol or 2-aminoethanol has been successfully developed under thermal and microwave conditions. By this two-component protocol, mono- and bis-oxazines and oxazolines were selectively synthesized both in good to excellent yields and short reaction times. This catalytic system exhibits excellent chemoselectivity, and can be reused at least seven times without significant loss of activity in subsequent reactions.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Haixia Ge, Ping Liu, Xiangnan Li, Wei Sun, Jianli Li, Bingqin Yang, Zhen Shi,