| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5218105 | Tetrahedron | 2013 | 7 Pages |
Abstract
The Staudinger reaction of imines to β-lactams was successfully achieved with substituted acetic acid and phosphonitrilic chloride in one-pot under mild conditions. Several types of β-lactams, especially 3-electron-withdrawing group β-lactams, can be synthesized by this versatile and efficient method in good to excellent yields. This method is simple, clean, and the by-products were removed by simple aqueous work-up. The effects of solvents, molar ratio of reagent, and the temperature were considered.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Maaroof Zarei,