Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5218250 | Tetrahedron | 2013 | 8 Pages |
Abstract
Aryl dialkyl phosphate, which is readily available from phenol, was a good substrate for the Pd(II) catalyzed aryl-aryl coupling reaction through ortho-C-H activation. Although a phosphate group is regarded as a poor coordinating group, highly regioselective ortho-arylation could be achieved by employing Pd(OTf)2·2H2O and Ar2IOTf as a catalyst and an aryl group source, respectively. The phosphate group of the resulting coupled product can be transformed into an aryl anion via reductive cleavage and used for further C-C bond formation.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Woo Hyung Jeon, Tae Seob Lee, Eun Jin Kim, Bongjin Moon, Jahyo Kang,