| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5218292 | Tetrahedron | 2013 | 10 Pages |
Abstract
In this paper we present new, monodentate phosphoramidite ligands based on amines derived from the easy available monosaccharide d-xylose and BINOLs. Ligands were used for copper-catalyzed conjugate addition to acyclic and cyclic enones. The highest enantioselectivity achieved in this study was 77% ee for the conjugate addition to trans-chalcone, which is comparable to the best results published to date for phosphoramidite ligands based on carbohydrate-derived amines.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tomasz Bauer, Maciej Majdecki, Janusz Jurczak,