Article ID Journal Published Year Pages File Type
5218315 Tetrahedron 2013 7 Pages PDF
Abstract

An In(OTf)3-catalyzed N-benzylation of amines utilizing benzyl alcohols through direct C-O bond activation has been reported. The reaction was performed in water without any base, additive, ligand or inert gas protection to afford the chem-selective mono- or bis-alkylated aromatic amines in good to excellent yields.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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