| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5218393 | Tetrahedron | 2013 | 9 Pages |
Abstract
Phosphinodepsipeptides are recognized as an important class of enzyme inhibitors as tetrahedrally structural transition-state analogues to natural peptides. A series of phosphinodepsipeptides was synthesized in satisfactory yields via pseudo-four-component condensation reaction of 2-(N-benzoxycarbonylamino)alkanamides/peptide amides, aldehydes, and aryldichlorophosphines, followed by alcoholysis with hydroxyl esters.
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