Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5218453 | Tetrahedron | 2013 | 6 Pages |
Abstract
The enantioselective addition of alcohols to isatin-derived N-Boc ketimines was investigated for the first time. Isatin-derived N,O-aminals were obtained in excellent yields with moderate-to-good enantioselectivities (up to 78% ee) in the presence of a quinine-based bifunctional catalyst.
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