Article ID Journal Published Year Pages File Type
5218453 Tetrahedron 2013 6 Pages PDF
Abstract

The enantioselective addition of alcohols to isatin-derived N-Boc ketimines was investigated for the first time. Isatin-derived N,O-aminals were obtained in excellent yields with moderate-to-good enantioselectivities (up to 78% ee) in the presence of a quinine-based bifunctional catalyst.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry