Article ID Journal Published Year Pages File Type
5218554 Tetrahedron 2013 6 Pages PDF
Abstract

The cyclization of fluoroalkylated 3,5-dioxoesters with hydrazines, carried out in glacial acetic acid, afforded pyrazines with fluoroalkylated side-chain. The cyclization of 3,5-dioxoesters with hydroxylamine afforded hydroxylated fluoroalkylated dihydroisoxazoles. All reactions proceeded with good to very good regioselectivity.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry