Article ID Journal Published Year Pages File Type
5218573 Tetrahedron 2013 7 Pages PDF
Abstract

An I2-promoted sp3 C–H functionalization has been developed for the synthesis of 2,5-disubstituted oxazoles from easily available methyl ketones and benzylamines without any metal and peroxide catalyst. This domino oxidative cyclization process involves the cleavage of C–H bond and the formation of C–N, C–O bonds.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry