| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5218603 | Tetrahedron | 2013 | 7 Pages |
Abstract
We report here the transformation of 3/5-trifluoromethylpyrazoles derivative into the corresponding NH-pyrazole-3/5-carboxylic acids. Moreover, from 4- or 5-iodinated-3/5-trifluoromethylpyrazoles building blocks and the use of Suzuki-Miyaura or Negishi reactions followed by the trifluoromethyl hydrolysis, we illustrate short and original accesses to many series of NH-pyrazole-3/5-carboxylic acids otherwise difficult to prepare.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mikhail S. Ermolenko, Sandrine Guillou, Yves L. Janin,