Article ID Journal Published Year Pages File Type
5218638 Tetrahedron 2013 8 Pages PDF
Abstract

Four-component coupling of amines, aldehydes, 1,3-dicarbonyl compounds, and nitromethane has been achieved in gluconic acid aqueous solution (GAAS) to produce polysubstituted pyrroles in high yield. Gluconic acid aqueous solution could be recycled and reused several times without significant loss of its efficiency.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry