| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5218740 | Tetrahedron | 2013 | 6 Pages |
Abstract
A general, efficient, and green method for one-pot synthesis of functionalized spirooxindoles through three-component condensation reaction of isatins, cyclohexane-1,3-diones, and barbituric acids is described employing gluconic acid aqueous solution (GAAS) as a novel reaction medium and catalyst. The reaction medium could be recycled and reused several times without significant loss of its efficiency.
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Related Topics
Physical Sciences and Engineering
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