Article ID Journal Published Year Pages File Type
5218788 Tetrahedron 2013 12 Pages PDF
Abstract

An enantiospecific total synthesis of indole alkaloids eburnamonine, aspidospermidine and quebrachamine is described from lactic acid. Synthesis of all three alkaloids is accomplished from a single chiral building block. Johnson-Claisen rearrangement of a chiral allyl alcohol is the main feature for the installation of the required quaternary centre.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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