Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5218835 | Tetrahedron | 2012 | 8 Pages |
Abstract
The stereoselective reaction of 4-oxoazetidine-2-carbaldehydes and their corresponding imines with cyanide-based reagents give β-lactam α-aminonitriles, which are chameleonic building blocks for the controlled synthesis of a variety of new compounds including functionalized γ-lactams, succinimide derivatives, and diamino-lactams derivatives in optically pure form.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Benito Alcaide, Pedro Almendros, Gema Cabrero, M. Pilar Ruiz,