| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5218877 | Tetrahedron | 2013 | 5 Pages |
Abstract
1-Iodo-3,4-dihydronaphthalene, an iodoalkene substrate obtained from α-tetralon, has been carbonylated in the presence of palladium-phosphine precatalysts. Systematic investigations have revealed that the 1-carboxamido-3,4-dihydronaphthalenes and 1-methoxycarbonyl-3,4-dihydronaphthalene have been formed in exceptionally high isolated yields (up to 96%) in chemospecific reaction. The influence of the amine nucleophile and that of the reaction conditions (carbon monoxide pressure, reaction temperature) on the reactivity of the substrate have been investigated.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Roland Farkas, Erik A. Molnár, Péter Ács, Attila Takács, László Kollár,