| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5218888 | Tetrahedron | 2013 | 6 Pages |
Abstract
N-Alkoxyalkylation of nucleobases was realized by the copper-catalyzed peroxide-promoted coupling of nucleobases with readily available saturated ethers. Both purines and pyrimidines could be N-alkoxyalkylated through this method in moderate to good yields. 2D-NMR revealed that N9-alkoxyalkylation preferentially occurred when purines were used in this reaction.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rui Huang, Chunsong Xie, Lin Huang, Jinhua Liu,