| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5218891 | Tetrahedron | 2013 | 5 Pages |
Abstract
An efficient synthetic route for novel nucleosides has been realized. We report the formation of α-isomers in spite of neighboring group participation by the benzoyl group at the 2-position in N-glycosidation as well as discuss the stereoselectivity observed. We also found that non-silylated pyrimidin-2(1H)-ones and pyrimidin-2(1H)-thiones having aromatic structures reacted with 1-fluororibose in the presence of a Lewis acid to give the corresponding nucleosides in good to high yield.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kyosuke Michigami, Satoshi Uchida, Miho Adachi, Masahiko Hayashi,