Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5218959 | Tetrahedron | 2012 | 7 Pages |
Abstract
Hydroperoxy compounds are important for selective oxidation of organic precursors in the chemical industry. Moreover, novel 3-hydroperoxyisothiazole 1,1-dioxides (N-phthalimidyl sultams) have been shown to be potent and specific inhibitors of acetylcholinesterase (AChE) an important enzyme in the neurotransmitter process. The inhibitory potential of these novel compounds is clearly linked to the hydroperoxide moiety. Hydroperoxides are known for their chemi- and thermochemiluminescent reactivity. In this study we tested thermochemiluminescence (TCL) as a fast method to detect and characterize the hydroperoxide moiety in structurally different synthetic organic hydroperoxides.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Matthias Gilbert, Valeria Zakharova, Anna Ramenda, Christian Jebsen, Bärbel Schulze, Christian Wilhelm,