| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219039 | Tetrahedron | 2012 | 9 Pages |
Abstract
Novel P-monodentate phosphite-type ligands have been synthesized in one step from BINOL mono-tosylate and BINOL mono-(â)-menthylcarbonate. The use of these ligands provides up to 96% ee in Pd-catalyzed asymmetric allylic substitution of (E)-1,3-diphenylallyl acetate and up to 99% ee in Rh-catalyzed asymmetric addition of phenylboronic acid to cyclohex-2-enone. The influence of the structural modules such as the nature of phosphorus-containing ring or exocyclic substituent on the enantioselectivity is discussed.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Konstantin N. Gavrilov, Sergey V. Zheglov, Mariya N. Gavrilova, Ivan M. Novikov, Marina G. Maksimova, Nikolay N. Groshkin, Eugenie A. Rastorguev, Vadim A. Davankov,