| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219093 | Tetrahedron | 2012 | 7 Pages |
Abstract
Application of bromoalkylalcohol and acrylate partners in a palladium/norbornene catalyzed domino direct alkylation/alkenylation of iodoarenes provides a new strategy for construction of biologically interesting ortho-hydroxyalkyl cinnamic acid alkyl esters. This protocol is compatible with a vide variety of electron-donating and -withdrawing substituents and allows one-pot construction of highly functionalized primary alcohols in high yields.
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