| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219100 | Tetrahedron | 2012 | 13 Pages |
Abstract
Good levels of 1,4-anti asymmetric induction are obtained in the TiCl3(i-PrO)-mediated aldol reaction of chiral α-benzyloxy methyl ketones with a wide array of aldehydes. This methodology represents a new approach to substrate-controlled acetate aldol reactions capable of providing highly functionalized fragments in a straightforward manner, which may be useful in the design of more efficient syntheses.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Miquel Pellicena, Joan G. Solsona, Pedro Romea, Fèlix UrpÃ,