Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219180 | Tetrahedron | 2012 | 7 Pages |
Abstract
An enantioselective access to (â)-indolizidine alkaloids 167B, 209D, 239AB, 195B and (â)-monomorine from a new chiral synthon is described. The use of (S)-3-(Cbz-amino)-4-(tert-butyldimethylsilyloxy)butanal, obtained from l-aspartic acid, has provided efficient access of the indolizidine frame work through a Horner-Wadsworth-Emmons reaction and reductive cyclization as the key steps.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chada Raji Reddy, Bellamkonda Latha, Nagavaram Narsimha Rao,